Introduction: Advanced stage Hodgkin lymphoma (ASHL) is still a major concern to face in both developed and developing countries. Five-year survival rate ranges between 51% and 94.6% in Western literature. However, few is known about the features of ASHL in developing countries. The purpose of this study is to describe the clinic-pathological features of ASHL in Morocco. Methods: Retrospective descriptive study of diagnosed ASHL carried over a period of 6.5 years from January 2007 to August 2013 in a single Moroccan University Hospital, including all patients with ASHL (stage III and IV of Ann Arbor) aged over 18. Patients with retroviral infections and secondary HL were excluded. The diagnosis was based on histological examination of biopsy and immunohistochemistry. Patients were classified according to the classification of Ann Arbor, and stratified according to the score of IPS. Results: Four hundred and seventy-eight patients were diagnosed with HL (all stages) during the period study, among them 200 patients ASHL account for 46.3. The age was ranged between 18 and 91 years old (yo) with a median age of 32 yo. Sex ratio H/F was 1.66. Seventy three percent of ASHL patients didn’t have medical insurance and 47% were jobless. the median time to diagnosis was 6 months [1-52]. Lymphadenopathy was the most common presentation (61.5%). Eighty three patients (41,5%) were stage III, 117 patients (58,5%) were stage IV. Eighty two percent of the patients reported B symptoms. Nodular sclerosis was the predominant histological presentation of ASHL in adult (60.5%) followed by mixed cellularity (17.5%). Ninety nine percent of lymphoma’s biopsies were CD30+, 82.5% were CD15+ and LMP-1 was positive in 33.6%. Bulky disease was present in 37% of the ASHL. IPS score was ranged between 0 and 6 with a median of 3, 42,5% patients had a score less than 2. Survival was rated in patients treated with 8 cycles of ABVD +/- Radiotherapy (150 patients fulfilled the inclusion criteria). Twenty-one percent of patients were treatment failure, 12% relapsed. The death rate was 20.6% of which 45% was by progression disease. The 5-years overall survival and event free survival of ASHL patients were 70,9% and 41,7% respectively. Conclusion: This current pattern for epidemiological features and outcomes of ASHL enables delineate key populations in order to explore risk factors for ASHL and strategies to improve treatment outcomes, especially intensification strategies.